Fluoxymesterone

$100 $93
Fluoxymesterone is an orally administered synthetic anabolic steroid derived from testosterone. More specifically, it is a derivative of methyltestosterone with the addition of 11-β-hydroxy and 9-α-fl

Performance

Strength Increase：

★★★★★

Muscle Gain：

★ ★★★★

Reduce Fat/Water：

★★★ ★★

Side Effects：

★★★★★

Sustained Effects：

★★ ★★★

SKU：

10mg/tablet × 100 tablets/bottle

Package：

tablet

Appearance：

oral

Dosage：

2-4 capsules per day

Cycle：

2–4 weeks

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Description:


Fluoxymesterone is a synthetic anabolic steroid taken orally and derived from testosterone. It is distinguished by the addition of 11-β-hydroxy and 9-α-fluoro groups to methyltestosterone, creating a potent, non-aromatizable oral steroid with strong androgenic characteristics. Fluoxymesterone has a much higher androgenic activity compared to testosterone; however, its anabolic effects are considered moderate. This makes fluoxymesterone primarily a drug for increasing strength rather than ideal for significant muscle mass gains. The primary effects of taking fluoxymesterone include increased strength, enhanced muscle density, and improved definition, but only moderate size increases.


History:


Fluoxymesterone first appeared in 1956 and was tested the same year, revealing its anabolic potency to be about 20 times that of methyltestosterone (though its relative anabolic effect in humans is not as strong). Known as Halotestin (by Upjohn) and later marketed as Ultandren (by Ciba), it was originally described as a halogenated derivative of testosterone with five times the anabolic and androgenic potency of methyltestosterone. Early prescription guidelines indicated its use for promoting lean tissue repair and growth in conditions such as burns, fracture healing delay, chronic malnutrition, debilitating diseases, paraplegia, or prolonged cortisone exposure. It was also used to treat male androgen deficiency and abnormal bleeding in uterine and advanced breast cancer in women.


By the mid-1970s, the FDA had increased control over the US drug market. One of the first major changes for steroid medications was the FDA's requirement for robust proof of potential drug benefits. The prescribing guidelines for fluoxymesterone were soon refined, affirming its efficacy for treating various forms of male androgen deficiency, reducing postpartum breast engorgement, and treating inoperable androgen-responsive breast cancer in women. It was also listed as a "possibly effective" treatment for postmenopausal osteoporosis. Currently, the prescribing guidelines for fluoxymesterone only list the treatment of male androgen deficiency and female breast cancer.


In recent years, fluoxymesterone has increasingly been viewed as a controversial drug by most clinical physicians. Its hepatotoxicity and potential negative impacts on lipid and cardiovascular risk factors often serve as reasons to prohibit its use in other healthy men for treating androgen deficiency. Today, testosterone preparations (injections, gels, patches, implants, etc.), which supplement the body's missing androgens (testosterone, DHT) without being more toxic synthetic derivatives, are generally preferred. Fluoxymesterone is still sold in the US but only as a generic drug, with limited availability outside the US.


Specifications Offered:


Fluoxymesterone is available on some human drug markets. Compositions and dosages may vary by country and manufacturer, although they are typically available in 2 mg, 2.5 mg, 5 mg, or 10 mg tablets.


Structural Characteristics:


Fluoxymesterone is a modified form of testosterone. Its distinctions include: 1) the addition of a methyl group at carbon 17-α to protect the hormone during oral administration, 2) the introduction of a fluorine group at carbon 9-α, and 3) the attachment of a hydroxyl group at carbon 11 (β), which inhibits steroid aromatization. These modifications also greatly enhance the steroid's androgenic and relative biological activity on 17-α-methyl testosterone.


Side Effects (Estrogenic):


Fluoxymesterone cannot be aromatized by the body and exhibits no estrogenic activity. Anti-estrogens are unnecessary when using this steroid, as gynecomastia will not be a concern for sensitive individuals. Since estrogens are a common cause of water retention, this steroid can produce a lean mass appearance without the concern for excess subcutaneous fluid retention. This makes it a favorable steroid during cutting cycles when water and fat retention are major concerns.


Side Effects (Androgenic):


Fluoxymesterone is classified as an androgen. Androgenic side effects are common when using this substance, which may include oily skin, acne, and body/facial hair growth. Synthetic anabolic/androgenic steroids can also exacerbate male pattern hair loss. Men genetically prone to male pattern baldness may need to choose milder, less androgenic anabolic steroids. As a potent androgen, this steroid may also increase aggressiveness. Women are also cautioned as synthetic anabolic/androgenic steroids pose potential virilizing effects. These may include deepening of the voice, menstrual irregularities, changes in skin texture, facial hair growth, and clitoral enlargement.


Fluoxymesterone appears to be a good substrate for 5-α-reductase. A large amount of its metabolites is found to be 5-α-reduced androgens, indicating that, similar to its outward androgenic properties, the steroid is being converted to more active steroids in androgen-responsive target tissues. Using finasteride or dutasteride can reduce the relative androgenicity of fluoxymesterone.


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